Benefits of Microdosing with The Stamets Stack

Benefits of Microdosing with The Stamets Stack

The Stamets Stack, named after mycologist Paul Stamets, combines various mushroom species to create a potent blend with potential health benefits. This stack typically includes lion’s mane, reishi, chaga, and cordyceps mushrooms. 

Inspired by traditional medicine practices and scientific research, the Stamets Stack aims to support cognitive function, immune system health, and overall well-being. As interest in natural remedies grows, the stamets stack has gained popularity for its potential synergistic effects and possibility of therapy as this.

If you wish to try Stamets Stack, do it under the guidance of a qualified medical professional and follow a schedule that fits your individual needs and tolerance.

Understanding Microdosing

Microdosing, the practice of consuming sub-perceptual amounts of psychedelics like psilocybin, is gaining popularity for its potential cognitive and mood-improving benefits. Users report increased focus, creativity, and emotional well-being without the intense psychedelic effects associated with regular dosing.

Who Is Paul Stamets

Stamets Stack is a popular combination of natural supplements, psilocybin, lion’s mane and niacin that is claimed to have a range of potential benefits for the mind and body. 

Stamets is perhaps best known for his work for the use of medicinal mushrooms to treat a range of health problems. They include cancer, Alzheimer’s and other diseases. He is also a strong advocate for the use of mushrooms in bioremediation or the use of living organisms to clean up pollution in the environment.

Stamets has received numerous honours and awards for his work, including National Geographic Adventure Magazine’s Green-O-Vator Award and the Society for Ecological Restoration’s President’s Award. 

He currently lives and works in Camilcea Point, Washington, where he runs Fungi Perfecti, a company that specializes in mushroom cultivation and mycological research.

Fungi Perfecti

As the founder of Fungi Perfecti, Stamets established a company that serves as a hub for mushroom cultivation and research. Fungi Perfecti is renowned for its commitment to producing high-quality mushroom products.

The company’s dedication to sustainable practices underscores its mission to promote the benefits of mushrooms for both human health and environmental well-being.

Stamets’ vision through Fungi Perfecti aligns with his belief in the profound impact that fungi can have on various aspects of life. Fungi Perfecti continues to be at the forefront of the fungi industry, driving innovation and promoting awareness about the therapeutic properties of mushrooms.

Stamets Stack

One of Paul Stamets’ most notable contributions to cognitive function is the development of the Stamets Stack. This unique blend combines several mushroom species, each known for its distinct benefits on brain health and cognitive performance. 

The Stamets Stack has gained popularity among individuals seeking to optimize their mental acuity and overall well-being through natural means. The Stamets Stack comprises a carefully selected combination of mushrooms, such as Lion’s Mane and Reishi, known for their neuroprotective properties and ability to support mental clarity.

Thinking long and hard, Stamets has provided a convenient and effective way for individuals to incorporate the benefits of various mushrooms into their daily routine, promoting brain function and overall cognitive wellness.

The Stamets Stack

The Stamets Stack refers to a combination of three: Psilocybin, Lion’s Mane, and Niacin. Each element of this cocktail is a boosting rung on the ladder of cognitive function and overall well-being.

Combination Rationale

Paul Stamets introduced this stack based on the idea of synergistic effects. By combining Lion’s Mane and Psilocybin, he aimed to amplify the benefits of both substances. The neurogenesis properties of Lion’s Mane complement the cognitive-enhancing effects of Psilocybin, creating a powerful blend for brain health.

Health benefits of niacin

Vitamin B3 is maintaining human health. It is involved in many processes in the body and can provide a number of potential benefits. Supporting cardiovascular health. Niacin helps lower “bad” cholesterol (LDL) and increase “good” cholesterol (HDL).

  • Maintain healthy skin — promotes the production of collagen, which makes skin firm and elastic. It also improves skin barrier function, reducing dryness, redness and other irritations
  • Supporting energy production — vitamin B3 is involved in the production of ATP, the molecule that provides energy to cells. Taking niacin can boost energy levels and reduce fatigue
  • Help with arthritis — has anti-inflammatory properties. It can help reduce joint pain and stiffness in people with arthritis

Vitamin B3 is involved in the production of serotonin, which regulates mood, sleep and appetite. Studies show that taking niacin can improve cognitive function and reduce symptoms of depression and anxiety.

Synergistic Effects

The Stamets Stack is believed to offer a range of benefits due to the unique properties of each component. Psilocybin works in tandem with Lion’s Mane, which promotes nerve growth and cognitive function. Niacin acts as a vasodilator and watches optimal blood flow for nutrient delivery.

When combined, the components of the Stamets Stack may lead to improved cognitive function by promoting neuroplasticity and synaptic growth. Users have reported experiencing heightened creativity and problem-solving abilities after incorporating this stack into their routine.

Future potential

As research on the Stamets Stack continues to evolve, scientists are delving deeper into understanding its mechanisms of action and long-term effects. With growing interest in natural remedies for mental health, this stack holds promise for those looking to optimize their brain function in a safe manner.

  • Lion’s Mane — one of the components of the Stamets Stack, known for its neuroprotective properties. This mushroom contains compounds that stimulate nerve growth factor (NGF) production
  • Psilocybin — another main element of the Stamets Stack, is a naturally occurring psychedelic compound found in certain mushrooms. It has gained attention for its potential to boost creativity, mood, and mental well-being
  • Niacin — also known as vitamin B3, plays a vital role in the Stamets Stack due to its ability to improve blood flow and circulation. Niacin with the help of vasodilation boosts the delivery of nutrients and oxygen to the brain, supporting overall cognitive function 

Role in Cognitive Functioning

The combination of Lion’s Mane, Psilocybin, and Niacin in the Stamets Stack creates a synergistic effect that targets various aspects of brain function. Lion’s Mane promotes nerve growth and cognitive function.

Psilocybin boosts creativity and mood. Niacin complements these effects by improving blood flow and reducing inflammation, further supporting cognitive benefit.

Potential benefits:

  • Improved memory retention and recall
  • Focus and concentration
  • Increased creativity and problem-solving abilities

Dosage Guidelines

Microdosing with a Stamets stack, it is evident to start with low doses. This way of doing things saves beginners tolerance and is quite a test-drive. Gradually increasing the dose of the Stamets stack is essential for finding the optimal dose that works best for each individual. 

This method, known as microdosing, involves taking small amounts of the stack regularly. Microdosing enables users to experience subtle benefits without overwhelming effects, making it easier to integrate into daily routines.

Consulting Healthcare Professionals

Before you start a Statements stack course, think about possible side effects and be sure to consult with medical professionals. Consulting a healthcare provider can help address any substance use concerns. Healthcare professionals can provide personalized recommendations based on individual needs and medical history.

Differentiating macro and microdosing

In the context of the Stamets stack, understanding the difference between macrodosing and microdosing is a question worth familiarizing yourself with in advance. Macrodosing involves taking larger amounts of the stack intermittently, often for more pronounced effects. 

Conversely, microdosing entails consuming smaller, sub-perceptual doses regularly to maintain a consistent level of benefits without significant psychoactive effects.

What’s about dosage?

Benefits of Microdosing with The Stamets Stack

Schedule Stamets Stack is a method of taking a combination of mushrooms and supplements developed by mycologist and author Paul Stamets. Stack contains three main ingredients: psilocybin mushrooms, lion’s mane mushroom, and niacin.

The dosage and schedule is as follows:

  • Psilocybin mushroom powder = 100 mg – 200 mg, or 0.1 – 0.3 grams of dried mushrooms
  • Lion’s mane = 50 – 100 mgNiacin = 100 – 200 mg

Day 1

Take a microdose, Lion’s Mane stack and niacin

Day 2

Take a microdose and Niacin stack
Day 3
Take a microdose, Lion’s Mane and Niacin stack
Day 4
Take a microdose, Lion’s Mane and Niacin stack

Day 5-7 Take a break from taking the stack

Repeat for four to six weeks, then make a break for two to six weeks. The addition of niacin is believed to boost the effects of psilocybin, and lion’s mane promotes neurogenesis and protects the brain. 

The intake schedule is designed to provide a synergistic effect between the three ingredients: niacin causes a rush of blood to the brain, and lion’s mane promotes the formation of nerve growth factors that can help counteract any potential negative effects of psilocybin.


As a side note, the use of psilocybin mushrooms is still illegal in many countries, and you can use it under the guidance of a doctor. In addition, although Stamets Stack has gained popularity in recent years, more research is needed. 

If you wish to try Stamets Stack, do it under the guidance of a qualified medical professional and follow a schedule that fits your individual needs and tolerance.

Funguyz provides high-quality shrooms and psilocybin edibles to consumers. They strongly support for the accessibility of dried shrooms’ therapeutic properties to everyone. If you seek premium products for microdosing, Funguyz is the go-to source for reliable and potent options.